Fatal SARS-CoV-2-Associated Panton-Valentine Leukocidin-producing Staphylococcal Bacteremia: A Nationwide Multicenter Cohort Study. Issue 4 (4th March 2022)

• Record Type: Journal Article
• Authors: Nygaard, Ulrikka; Petersen, Andreas; Larsen, Anders Rhod; Rytter, Maren Johanne Heilskov; Hartling, Ulla; Kirkby, Nikolai; Hansen, Rikke Nymark; Nielsen, Allan Bybeck; Lundstrøm, Kaare; Holm, Mette; Vissing, Nadja Hawwa
• Is Part Of: Pediatric infectious disease journal. Volume 41:Issue 4(2022)
• Page Start: e142
• Page End: e145
• Publication Date: 2022-03-04
• Subjects: Panton-Valentine leukocidin -- Staphylococcus aureus -- SARS-CoV-2; Communicable diseases in children -- Periodicals; Infection in children -- Periodicals; 618.929
• DOI: 10.1097/INF.0000000000003476
• Languages: English
• ISSNs: 0891-3668

Abstract

Abstract : We reviewed all cases of Panton-Valentine leukocidin-producing Staphylococcus aureus (PVL-SA) bacteremia in Danish children between 2016 and 2021. We found 2 fatal cases with preceding viral prodrome due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Given the usual benign course of SARS-CoV-2 infection in children, awareness of possible superinfection with PVL-SA in a child with rapid deterioration is crucial to ensure adequate treatment, including antimicrobial drugs with antitoxin effect.