Current status of photodynamic technology for urothelial cancer. Issue 2 (2nd December 2021)
- Record Type:
- Journal Article
- Title:
- Current status of photodynamic technology for urothelial cancer. Issue 2 (2nd December 2021)
- Main Title:
- Current status of photodynamic technology for urothelial cancer
- Authors:
- Inoue, Keiji
Fukuhara, Hideo
Yamamoto, Shinkuro
Karashima, Takashi
Kurabayashi, Atsushi
Furihata, Mutsuo
Hanazaki, Kazuhiro
Lai, Hung Wei
Ogura, Shun‐Ichiro - Abstract:
- Abstract: 5‐Aminolevulinic acid is a new‐generation photosensitizer with high tumor specificity. It has been used successfully in the diagnosis, treatment, and screening of urological cancers including bladder cancer; specifically, it has been used in photodynamic diagnosis to detect tumors by illuminating the lesion with a specific wavelength of light to produce fluorescence in the lesion after administration of 5‐aminolevulinic acid, in photodynamic therapy, which induces tumor cell death via production of cytotoxic reactive oxygen species, and in photodynamic screening, in which porphyrin excretion in the blood and urine is used as a tumor biomarker after administration of 5‐aminolevulinic acid. In addition to these applications in urological cancers, 5‐aminolevulinic acid–based photodynamic technology is expected to be used as a novel strategy for a large number of cancer types because it is based on a property of cancer cells known as the Warburg effect, which is a basic biological property that is common across all cancers. Abstract : The mechanism of 5‐aminolevulinic acid‐based photodynamic therapy.
- Is Part Of:
- Cancer science. Volume 113:Issue 2(2022)
- Journal:
- Cancer science
- Issue:
- Volume 113:Issue 2(2022)
- Issue Display:
- Volume 113, Issue 2 (2022)
- Year:
- 2022
- Volume:
- 113
- Issue:
- 2
- Issue Sort Value:
- 2022-0113-0002-0000
- Page Start:
- 392
- Page End:
- 398
- Publication Date:
- 2021-12-02
- Subjects:
- Cancer -- Periodicals
Neoplasms -- Periodicals
Research -- Periodicals
Electronic journals
616.994005 - Journal URLs:
- http://firstsearch.oclc.org ↗
http://firstsearch.oclc.org/journal=1347-9032;screen=info;ECOIP ↗
http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1349-7006 ↗
http://onlinelibrary.wiley.com/ ↗ - DOI:
- 10.1111/cas.15193 ↗
- Languages:
- English
- ISSNs:
- 1347-9032
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3046.603000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 20758.xml