Impact of night and shift work on metabolic syndrome and its components: a cross-sectional study in an active middle-to-older-aged population-based sample. Issue 2 (15th February 2022)

• Record Type: Journal Article
• Authors: Bayon, Virginie; Berger, Mathieu; Solelhac, Geoffroy; Haba-Rubio, José; Marques-Vidal, Pedro; Strippoli, Marie-Pierre; Preisig, Martin; Leger, Damien; Heinzer, Raphael
• Is Part Of: BMJ open. Volume 12:Issue 2(2022)
• Publication Date: 2022-02-15
• Subjects: general endocrinology -- epidemiology -- diabetes & endocrinology; Medicine -- Research -- Periodicals; 610.72
• DOI: 10.1136/bmjopen-2021-053591
• Languages: English
• ISSNs: 2044-6055

Abstract

Abstract : Objectives: To examine the effects of work schedules on metabolic syndrome and its components in active middle-to-older-aged workers. Methods: A cross-sectional analysis including middle-to-older-aged active workers from the population-based CoLaus|PsyCoLaus study (Lausanne, Switzerland) was performed. Work schedule was self-reported and defined as follows: permanent day, day shift, night shift and permanent night work. Associations between work schedule and the risk of metabolic syndrome and its components were analysed using multivariable-adjusted logistic regressions. Results: A total of 2301 active workers (median age (IQR): 55.4 (50.8 to 60.4), 50.1% women) were included. Of these, 1905 were permanent day workers, 220 were day-shift workers, 134 were night-shift workers and 42 were permanent night-shift workers. There were significant interactions between sex and work schedule for metabolic syndrome, high triglycerides and visceral obesity. Men but not women permanent night workers had a higher prevalence of metabolic syndrome than permanent day workers in multivariable-adjusted analyses (OR 4.45 (95% CI 1.36 to 14.56)). Analysis of metabolic syndrome subcomponents showed that the association between work schedule and metabolic syndrome in men was mainly driven by visceral obesity (OR 3.35 (95% CI 1.04 to 10.76)). Conversely, women but not men working in night shift were at increased risk of having high triglycerides compared with permanent day workers (OR 2.92 (95% CI 1.03 to 8.27)). Conclusions: The risk of metabolic syndrome is higher in men working in permanent night shift compared with permanent day work, and this association could be mediated by visceral obesity.