Encapsulation of l-valine, d-leucine and d-methionine by cucurbit[8]uril. Issue 5 (12th January 2022)

• Record Type: Journal Article
• Authors: Zhang, Zeng-Hui; Lin, Rui-Lian; Yu, Xiang-Yun; Chen, Li-Xia; Tao, Zhu; Xiao, Xin; Wei, Gang; Redshaw, Carl; Liu, Jing-Xin
• Is Part Of: CrystEngComm. Volume 24:Issue 5(2022)
• Page Start: 1035
• Page End: 1040
• Publication Date: 2022-01-12
• Subjects: Crystals -- Periodicals; Crystal growth -- Periodicals; Crystallography -- Periodicals; Cristaux -- Périodiques; Cristaux -- Croissance -- Périodiques; Cristallographie -- Périodiques; 548
• DOI: 10.1039/d1ce01513c
• Languages: English
• ISSNs: 1466-8033

Abstract

Abstract : The binding interactions of cucurbit[8]uril (Q[8]) with l -valine, d -leucine, and d -methionine, both in aqueous solution and solid state, have been studied by 1 H NMR spectroscopy and X-ray crystallography. Abstract : The binding interactions of cucurbit[8]uril (Q[8]) with l -valine, d -leucine, and d -methionine, both in aqueous solution and solid state, have been studied by 1 H NMR spectroscopy and X-ray crystallography. 1 H NMR data indicate that Q[8] can encapsulate these three kinds of amino acids in aqueous solution. X-ray crystallography reveals how the Q[8] binds with the amino acids to form inclusion complexes l -Val2 @Q[8], d -Leu2 @Q[8], and d -Met2 @Q[8] through host-guest interactions. It was also found that the deformation degree of the Q[8] host is related to the molecular size of the encapsulated guests.