Rapid colorimetric discrimination of cyanide ions – mechanistic insights and applications. Issue 5 (14th January 2022)

• Record Type: Journal Article
• Authors: Kathiravan, Arunkumar; Sengottiyan, Selvaraj; Puzyn, Tomasz; Gopinath, Pushparathinam; Ramasubramanian, Kanagachidambaresan; Susila, Praveen Ayyappan; Jhonsi, Mariadoss Asha
• Is Part Of: Analytical methods. Volume 14:Issue 5(2022)
• Page Start: 518
• Page End: 525
• Publication Date: 2022-01-14
• Subjects: Chemistry, Analytic -- Periodicals; Analytical biochemistry -- Periodicals; Chemical laboratories -- Standards -- Periodicals; 543.1905
• DOI: 10.1039/d1ay02040d
• Languages: English
• ISSNs: 1759-9660

Abstract

Abstract : This work successfully demonstrated an intramolecular charge transfer-based colorimetric probe for the rapid naked-eye detection of cyanide ions in solution as well as in spiked-samples. Abstract : In this work, we have employed an intramolecular charge transfer-based DMN colorimetric probe for the rapid naked-eye detection of cyanide ions in solution as well as real water samples. The intermolecular interaction between the DMN probe and cyanide ions in solution was investigated using a combination of spectroscopic and computational methods in this study. The DMN probe exhibited a selective colorimetric response for cyanide ions over the other anions exposed. The cyanide sensing mechanism of the probe has been investigated by 1 H NMR titration and density functional theory calculations. The results reveal that the colorimetric response of the DMN probe is due to the Michael adduct formation in the β-conjugated position of the dicyanovinyl group with cyanide, which blocks intramolecular charge transfer transition. Under optimized experimental conditions, the DMN probe showed a linear plot in the concentration range of 0.01–0.25 μM, with a detection limit of 23 nM. Further, a 3D printed portable accessory for the smartphone and an open-source android application is developed to suit the DMN probe for on-site work. In addition, we have developed the microfluidic paper-based analytical device that could selectively detect cyanide ions at very low concentration using a colorimetric DMN probe. In addition, the DMN probe was effectively used to determine the cyanide ion in a variety of water samples.