Lower-Resolution Retrieval of Scenes in Older Adults With Subjective Cognitive Decline. (2nd August 2021)

• Record Type: Journal Article
• Authors: Ruiz-Rizzo, Adriana L; Pruitt, Patrick J; Finke, Kathrin; Müller, Hermann J; Damoiseaux, Jessica S
• Is Part Of: Archives of clinical neuropsychology. Volume 37:Number 2(2022)
• Page Start: 408
• Page End: 422
• Publication Date: 2021-08-02
• Subjects: Memory encoding -- Memory retrieval -- Older adults -- Parahippocampal place area -- Scene complexity -- Subjective cognitive decline; Clinical neuropsychology -- Periodicals; 616.805
• DOI: 10.1093/arclin/acab061
• Languages: English
• ISSNs: 0887-6177

Abstract

Abstract: Objective: Scenes with more perceptual detail can help detect subtle memory deficits more than scenes with less detail. Here, we investigated whether older adults with subjective cognitive decline (SCD) show less brain activation and more memory deficits to scenes with more (vs. scenes with less) perceptual detail compared to controls (CON). Method: In 37 healthy older adults (SCD: 16), we measured blood oxygenation level-dependent-functional magnetic resonance imaging during encoding and behavioral performance during retrieval. Results: During encoding, higher activation to scenes with more (vs. less) perceptual detail in the parahippocampal place area predicted better memory performance in SCD and CON. During retrieval, superior performance for new scenes with more (vs. less) perceptual detail was significantly more pronounced in CON than inSCD. Conclusions: Together, these results suggest a present, but attenuated benefit from perceptual detail for memory retrieval in SCD. Memory complaints in SCD might, thus, refer to a decreased availability of perceptual detail of previously encoded stimuli.