Histology of hereditary neuralgic amyotrophy. Issue 3 (16th February 2005)

• Record Type: Journal Article
• Authors: van Alfen, N; Gabreëls-Festen, A A W M; ter Laak, H J; Arts, W F M; Gabreëls, F J M; van Engelen, B G M
• Is Part Of: Journal of neurology, neurosurgery and psychiatry. Volume 76:Issue 3(2005)
• Page Start: 445
• Page End: 447
• Publication Date: 2005-02-16
• Subjects: HNA, hereditary neuralgic amyotrophy -- HNPP, hereditary neuropathy with liability to pressure palsies -- NSPV, peripheral nervous system vasculitis; brachial plexus -- hereditary neuralgic amyotrophy -- histology; Neurology -- Periodicals; Nervous system -- Surgery -- Periodicals; Psychiatry -- Periodicals; 616.8
• DOI: 10.1136/jnnp.2004.044370
• Languages: English
• ISSNs: 0022-3050

Abstract

Abstract : We report the findings in five muscle and three sural nerve biopsies, and in one postmortem plexus specimen, from six patients with hereditary neuralgic amyotrophy (HNA). We found that the sensory nerves are definitely involved in HNA despite the mainly motor symptoms, and that lesions in nerves and muscles are more widespread throughout the peripheral nervous system than clinically presumed, but, simultaneously, very focally affect isolated fascicles within individual nerves.