Beta glucuronidase and hyperbilirubinaemia in breast fed infants of diabetic mothers. Issue 1 (January 1992)

• Record Type: Journal Article
• Authors: Sirota, L; Ferrera, M; Lerer, N; Dulitzky, F
• Is Part Of: Archives of disease in childhood. Volume 67:Issue 1(1992)
• Page Start: 120
• Page End: 121
• Publication Date: 1992-01
• Subjects: Children -- Diseases -- Periodicals; Infants -- Diseases -- Periodicals; 618.920005
• DOI: 10.1136/adc.67.1.120
• Languages: English
• ISSNs: 0003-9888

Abstract

Abstract : A prospective study was performed comparing bilirubin concentrations in 10 breast fed term infants of diabetic mothers (IDM) to those of 10 breast fed normal term infants. The beta-glucuronidase concentrations in serum and breast milk were assayed in the respective mothers. Significantly higher bilirubin concentrations were noted in the IDM group. Serum and breast milk beta-glucuronidase concentrations were significantly higher in diabetic mothers as compared with those of non-diabetic mothers. We suggest that the high concentration of beta-glucuronidase in breast milk of diabetic mothers is an additional important cause leading to hyperbilirubinaemia in their breast fed infants.