Outcomes of critically ill COVID-19 patients managed in a high-volume severe respiratory failure and ECMO centre in the United Kingdom. (May 2022)

• Record Type: Journal Article
• Authors: Sherren, Peter B; Camporota, Luigi; Sanderson, Barnaby; Jones, Andrew; Shankar-Hari, Manu; Meadows, Chris IS; Barrett, Nicholas; Ostermann, Marlies; Hart, Nicholas
• Is Part Of: Journal of the Intensive Care Society. Volume 23:Number 2(2022)
• Page Start: 233
• Page End: 236
• Publication Date: 2022-05
• Subjects: SARS-CoV-2 -- COVID-19 -- respiratory failure -- ARDS -- ventilation; Critical care medicine -- Periodicals; Intensive care units -- Periodicals; 616.028
• DOI: 10.1177/1751143720978850
• Languages: English
• ISSNs: 1751-1437

Abstract

During the Coronavirus Disease 2019 (COVID-19) pandemic institutions have needed to develop pragmatic clinical pathways to balance the excess critical care demand and local resources. In this single-centre retrospective cohort study we describe the outcomes of COVID-19 patients admitted to Guy's and St. Thomas' NHS Foundation Trust (GSTT) critical care service. Patients were managed according to a local respiratory failure management pathway that was predicated on timely invasive ventilation when indicated and tailored ventilatory strategies according to pulmonary mechanics. Between 2 March and 25 May 2020 GSTT critical care service admitted 316 patients with confirmed COVID-19. Of the 201 patients admitted directly through the Emergency Department (ED) with a completed critical care outcome, 71.1% survived to critical care discharge. These favourable outcomes may serve to inform the wider debate on optimal organ support in COVID-19.