A Problematic Biomarker Trial Design. (21st July 2021)
- Record Type:
- Journal Article
- Title:
- A Problematic Biomarker Trial Design. (21st July 2021)
- Main Title:
- A Problematic Biomarker Trial Design
- Authors:
- Freidlin, Boris
Korn, Edward L - Abstract:
- Abstract: Efficient biomarker-driven randomized clinical trials are a key tool for implementing precision oncology. A commonly used biomarker phase III design is focused on testing the treatment effect in biomarker-positive and overall study populations. This approach may result in recommending new treatments to biomarker-negative patients when these treatments have no benefit for these patients.
- Is Part Of:
- Journal of the National Cancer Institute. Volume 114:Number 2(2022)
- Journal:
- Journal of the National Cancer Institute
- Issue:
- Volume 114:Number 2(2022)
- Issue Display:
- Volume 114, Issue 2 (2022)
- Year:
- 2022
- Volume:
- 114
- Issue:
- 2
- Issue Sort Value:
- 2022-0114-0002-0000
- Page Start:
- 187
- Page End:
- 190
- Publication Date:
- 2021-07-21
- Subjects:
- Cancer -- Periodicals
Cancer -- Research -- Periodicals
616.994 - Journal URLs:
- https://jnci.oxfordjournals.org/ ↗
http://ukcatalogue.oup.com/ ↗ - DOI:
- 10.1093/jnci/djab144 ↗
- Languages:
- English
- ISSNs:
- 0027-8874
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 4830.000000
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 20702.xml