Twelve-Month Follow-up of Early COVID-19 Cases in the United States: Cellular and Humoral Immune Longevity. (5th January 2022)

• Record Type: Journal Article
• Authors: Shah, Melisa M; Rasheed, Mohammad Ata Ur; Harcourt, Jennifer L; Abedi, Glen R; Stumpf, Megan M; Kirking, Hannah L; Tamin, Azaibi; Mills, Lisa; Armstrong, Madeleine; Salvatore, Phillip P; Surasi, Krishna; Scott, Sarah E; Killerby, Marie E; Briggs-Hagen, Melissa; Saydah, Sharon; Tate, Jacqueline E; Fry, Alicia M; Hall, Aron J; Thornburg, Natalie J; Midgley, Claire M
• Is Part Of: Open forum infectious diseases. Volume 9:Number 3(2022)
• Publication Date: 2022-01-05
• Subjects: COVID-19 -- immunity -- memory B cells -- SARS-CoV-2 infection; Communicable diseases -- Periodicals; Medical microbiology -- Periodicals; Infection -- Periodicals; 616.9
• DOI: 10.1093/ofid/ofab664
• Languages: English
• ISSNs: 2328-8957

Abstract

Abstract: We quantify antibody and memory B-cell responses to severe acute respiratory syndrome coronavirus 2 at 6 and 12 months postinfection among 7 unvaccinated US coronavirus disease 2019 cases. All had detectable S-specific memory B cells and immunoglobulin G at both time points, with geometric mean titers of 117.2 BAU/mL and 84.0 BAU/mL at 6 and 12 months, respectively.