MR imaging features of Lhermitte–Duclos disease: Case reports and literature review. Issue 4 (28th January 2022)

• Record Type: Journal Article
• Authors: Zhang, Han-wen; Zhang, Yuan-qing; Liu, Xiao-lei; Mo, Yong-qian; Lei, Yi; Lin, Fan; Feng, Yu-ning
• Editors: Saranathan., Maya
• Is Part Of: Medicine. Volume 101:Issue 4(2022)
• Page Start: e28667
• Publication Date: 2022-01-28
• Subjects: Lhermitte–Duclos disease -- MRI -- MRS -- posterior fossa -- PWI -- SWI; Medicine -- Periodicals; Medicine -- Periodicals; Médecine -- Périodiques; Geneeskunde; Medicine; Periodicals; Periodicals; 610.5
• DOI: 10.1097/MD.0000000000028667
• Languages: English
• ISSNs: 0025-7974

Abstract

Abstract: Rationale: Lhermitte–Duclos disease (LDD) is a rare tumor of the nervous system with a typical "tiger striped'" sign, but its features on functional magnetic resonance imaging (fMRI) are still inconclusive. Patient concerns: To explore the characteristics of LDDs using fMRI. Diagnoses: We report 3 cases of pathologically confirmed LDDs. Interventions: Three patients underwent brain tumor surgery. Outcomes: All the patients had a good prognosis. Lessons: Magnetic resonance spectroscopy and susceptibility-weighted imaging combined with conventional MRI can be used to better diagnose LDDs. Perfusion-weighted imaging is not specific for distinguishing cerebellar tumors. The combined application of fMRI and conventional MRI can improve the accuracy of LDD diagnoses.