Peripheral venous catheter colonization after skin disinfection with 0.5% aqueous sodium hypochlorite, preceded or not by one application of 70% ethanol (DACLEAN): a single-centre, randomized, open-label, pilot study. (February 2022)

• Record Type: Journal Article
• Authors: Drugeon, B.; Pichon, M.; Marjanovic, N.; Mousse, S.; Seguin, S.; Raynaud, C.; Rahoui, A.; Frasca, D.; Mimoz, O.; Guenezan, J.
• Is Part Of: Journal of hospital infection. Volume 120(2022)
• Page Start: 123
• Page End: 126
• Publication Date: 2022-02
• Subjects: Skin disinfection -- Antiseptic -- Vascular catheter -- Prevention -- Infection; Cross infection -- Periodicals; Cross infection -- Prevention -- Periodicals; Nosocomial infections -- Periodicals; Nosocomial infections -- Prevention -- Periodicals; Cross Infection -- Periodicals; Cross Infection -- prevention & control -- Periodicals; Infection Control -- Periodicals; Electronic journals; 614.44
• DOI: 10.1016/j.jhin.2021.11.012
• Languages: English
• ISSNs: 0195-6701

Abstract

Summary: Few data are available on the efficacy of 0.5% aqueous sodium hypochlorite (SH) for skin disinfection before peripheral catheter insertion. A total of 239 patients were randomly assigned to either one application of SH alone or one application of SH preceded by one application of 70% ethanol (ET-SH). Catheter colonization, defined as a catheter tip culture growing >1000 cfu of a micro-organism per millilitre, occurred in 29 patients (33% of 89 colonizations per 1000 catheter-days) in the SH group and in 31 patients (33% of 126 colonizations per 1000 catheter-days) in the ET-SH group.