Enantioselective NiH‐Catalyzed Reductive Hydrofunctionalization of Alkenes. Issue 5 (13th January 2022)

• Record Type: Journal Article
• Authors: He, Yuli; Chen, Jian; Jiang, Xiaoli; Zhu, Shaolin
• Is Part Of: Chinese journal of chemistry. Volume 40:Issue 5(2022)
• Page Start: 651
• Page End: 661
• Publication Date: 2022-01-13
• Subjects: Asymmetric catalysis -- Nickel catalysis -- Nickel hydride -- Hydrofunctionalization -- Alkene; Chemistry -- Periodicals; 540.5
• DOI: 10.1002/cjoc.202100763
• Languages: English
• ISSNs: 1001-604X

Abstract

Comprehensive Summary: Enantioselective NiH‐catalyzed reductive hydrofunctionalization of olefins has attracted much attention in recent years. Using simple chiral ligands, a wide array of functionalized olefins and electrophiles can undergo diverse transformations to afford hydrofunctionalized products, regio‐ and enantioselectively. These processes avoid the prior preparation of organometallic reagents, and can construct a stereogenic center at a carbon originating either from the olefin or from the electrophile. This review discusses the background, major progress and mechanistic investigations in this reaction. Abstract :