Pd-Catalyzed coupling of benzyl bromides with BMIDA-substituted N-tosylhydrazones: synthesis of trans-alkenyl MIDA boronates. Issue 3 (15th December 2021)

• Record Type: Journal Article
• Authors: Li, Shichao; Li, Muyao; Li, Shu-Sen; Wang, Jianbo
• Is Part Of: Chemical communications. Volume 58:Issue 3(2022)
• Page Start: 399
• Page End: 402
• Publication Date: 2021-12-15
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/d1cc06170d
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : A series of trans -alkenyl MIDA boronates have been prepared by palladium-catalyzed cross-coupling reaction of N -methyliminodiacetyl boronate (BMIDA)-substituted N -tosylhydrazone and benzyl bromides. Abstract : A palladium-catalyzed stereoselective synthesis of alkenyl boronates from N -methyliminodiacetyl boronate (BMIDA)-substituted N -tosylhydrazone and benzyl bromides is developed. A range of trans -alkenyl MIDA boronates as single stereoisomers were obtained in moderate yields with good functional group compatibility. The resultant boronate products may be transformed to other boron-containing compounds and may also be directly used in cross-coupling reactions.