Memory efficiency in patients with drug-resistant epilepsy. Issue 1 (2nd January 2022)

• Record Type: Journal Article
• Authors: Kunić, Suljo; Ibrahimagić, Omer Ć.; Vujković, Zoran; Đajić, Vlado; Smajlović, Dževdet; Mirković – Hajdukov, Mitra; Bećirović, Elvir; Kunić, Amela; Tupković, Emir
• Is Part Of: Acta clinica belgica. Volume 77:Issue 1(2022)
• Page Start: 25
• Page End: 29
• Publication Date: 2022-01-02
• Subjects: Epilepsy -- memory -- wechsler Memory Scale -- international League Against Epilepsy; Clinical medicine -- Periodicals; Diagnosis, Laboratory -- Periodicals; 616.005
• DOI: 10.1080/17843286.2020.1778347
• Languages: English
• ISSNs: 1784-3286

Abstract

ABSTRACT: Objective: To evaluate memory in patients with drug-resistant epilepsy. Methods: Following an examination, 50 patients were diagnosed in accordance with the 2005 proposal of the International League Against Epilepsy and the definition of drug-resistant epilepsy from 2010. The neuropsychological examination used the Wechsler Memory Scale. It assessed seven structural types of memory: general knowledge, orientation, mental control, logical memory, number memory, associative memory, and visual reproduction. The values were compared with 50 subjects without epilepsy. Results: Patients with epilepsy had statistically significantly lower values in five of seven structural units of memory. The average value of overall memory efficacy in subjects with epilepsy was 96.5 ± 19.6, while in subjects without epilepsy it was 118 ± 15.6 (p = 0.0002). Memory impairments are greater in those taking polytherapy (p = 0.0429). The overall memory efficiency correlated significantly negatively with seizure frequency (p = 0.0015) and insignificantly negative with the duration of epilepsy (p = 0.1935). Conclusion: Patients with drug-resistant epilepsy have lower memory efficiency. Memory impairments are greater in those taking polytherapy, as with those with more frequent seizures. The duration of epilepsy has no significant effect on overall memory performance.