A report of two cases of myocarditis following mRNA coronavirus disease 2019 vaccination. Issue 1 (9th January 2022)

• Record Type: Journal Article
• Authors: Bengel, Christopher Paul; Kacapor, Rifat
• Editors: Bromage, Daniel; Paratz, Elizabeth; Carrizales Sepulveda, Edgar Francis; Parollo, Matteo; Chakir, Mariame
• Is Part Of: European heart journal. Volume 6:Issue 1(2022)
• Publication Date: 2022-01-09
• Subjects: COVID-19 -- Vaccine -- Myocarditis -- Adverse reaction -- Case report; Cardiology -- Periodicals; Cardiology -- Case studies -- Periodicals; Heart -- Diseases -- Periodicals; Heart -- Diseases -- Case studies -- Periodicals; 616.12
• DOI: 10.1093/ehjcr/ytac004
• Languages: English
• ISSNs: 2514-2119

Abstract

Abstract: Background: Vaccination is the most important measure to control the coronavirus disease 2019 (COVID-19) pandemic. Myocarditis has been reported as a rare adverse reaction to COVID-19 vaccines. The clinical presentation of myocarditis in such cases can range from mild general symptoms to acute heart failure. Case summary: We report the cases of two young men who presented with chest pain and dyspnoea following the administration of the mRNA COVID-19 vaccine. Cardiac investigations revealed findings typical of acute myocarditis. Discussion: Myocarditis is a rare complication following mRNA COVID-19 vaccination. In this case series, the temporal proximity of the development of acute myocarditis and the administration of the mRNA COVID-19 vaccine was acknowledged. In the absence of other causative factors, myocarditis in these patients potentially occurred due to an adverse reaction to the mRNA COVID-19 vaccine. However, a causal relationship remains speculative. Clinical suspicion of myocarditis should be high if patients present with chest pain or dyspnoea after receiving COVID-19 vaccination.