Yeast synthetic biology advances biofuel production. (February 2022)

• Record Type: Journal Article
• Authors: Liu, Zihe; Wang, Junyang; Nielsen, Jens
• Is Part Of: Current opinion in microbiology. Volume 65(2022)
• Page Start: 33
• Page End: 39
• Publication Date: 2022-02
• Subjects: Microbiology -- Periodicals; 579.05
• DOI: 10.1016/j.mib.2021.10.010
• Languages: English
• ISSNs: 1369-5274

Abstract

Highlights: Biofuels represent valuable alternatives to fossil fuels to reduce net CO2 emission. S. cerevisiae is a widely used chassis with many available synthetic biology tools. Synthetic biology advances biofuel production in a more precise and efficient manner. Continuous developments are still necessary to streamline biofuel production. Abstract : Increasing concerns of environmental impacts and global warming calls for urgent need to switch from use of fossil fuels to renewable technologies. Biofuels represent attractive alternatives of fossil fuels and have gained continuous attentions. Through the use of synthetic biology it has become possible to engineer microbial cell factories for efficient biofuel production in a more precise and efficient manner. Here, we review advances on yeast-based biofuel production. Following an overview of synthetic biology impacts on biofuel production, we review recent advancements on the design, build, test, learn steps of yeast-based biofuel production, and end with discussion of challenges associated with use of synthetic biology for developing novel processes for biofuel production.