Defeating Bluetongue virus: new approaches in the development of multiserotype vaccines. (July 2016)

• Record Type: Journal Article
• Authors: Marín-López, Alejandro; Barriales, Diego; Moreno, Sandra; Ortego, Javier; Calvo-Pinilla, Eva
• Is Part Of: Future virology. Volume 11:Number 7(2016)
• Page Start: 535
• Page End: 548
• Publication Date: 2016-07
• Subjects: Bluetongue virus -- multiserotype protection -- vaccines -- virus variability; Virology -- Periodicals; Virus diseases -- Treatment -- Periodicals; 616.9101
• DOI: 10.2217/fvl-2016-0061
• Languages: English
• ISSNs: 1746-0794

Abstract

Bluetongue virus (BTV) is a global threat to domestic and wild ruminants, causing massive economic losses throughout the world. New serotypes of the virus are rapidly emerging in different continents, unfortunately there is little cross-protection between BTV serotypes. The eradication of the virus from a region is particularly complicated in areas where multiple serotypes circulate for a long time. The present review summarizes the actual concerns about the spread of the virus and relevant approaches to develop efficient vaccines against BTV, in particular those focused on a multiserotype design.