The impact of dementia on antidiabetic drug use in Medicare beneficiaries with diabetes: findings post-Medicare part D. (July 2016)

• Record Type: Journal Article
• Authors: Lu, Z Kevin; Li, Minghui; McGee, Karen; Phillips, Cynthia M; Yuan, Jing; Sutton, S Scott
• Is Part Of: Journal of comparative effectiveness research. Volume 5:Number 4(2016)
• Page Start: 383
• Page End: 392
• Publication Date: 2016-07
• Subjects: Alzheimer's disease -- antidiabetic drugs -- dementia -- Medicare -- vascular dementia; Medical care -- Research -- Periodicals; Medical care -- Research -- Evaluation -- Periodicals; Medical care -- Decision making -- Periodicals; Evidence-based medicine -- Periodicals; Medicine, Comparative -- Periodicals; 362.1072
• DOI: 10.2217/cer-2015-0006
• Languages: English
• ISSNs: 2042-6305

Abstract

Aim: The objectives of the study were to measure the utilization rates of antidiabetic drugs in diabetic patients with dementia and to assess the impact of dementia on antidiabetic drug use.Materials & methods: This study was a pooled cross-sectional study of the Medicare Current Beneficiaries Survey from 2006 to 2010.Results & conclusion: Lower utilizations of biguanides, DPP-4 inhibitors and thiazolidinediones were observed in dementia patients. The likelihood of using antidiabetic drugs was about 30% (odds ratio: 0.69; 95% CI: 0.56–0.84) lower in dementia patients and 40% (odds ratio: 0.61; 95% CI: 0.44–0.84) lower in patients with Alzheimer's disease. Healthcare providers should be aware of underuse of antidiabetic drugs in patients with dementia.