ViralEpi v1.0: a high-throughput spectrum of viral epigenomic methylation profiles from diverse diseases. (January 2016)

• Record Type: Journal Article
• Authors: Khan, Mohd Shoaib; Gupta, Amit Kumar; Kumar, Manoj
• Is Part Of: Epigenomics. Volume 8:Number 1(2016)
• Page Start: 67
• Page End: 75
• Publication Date: 2016-01
• Subjects: biomarkers -- CpG dinucleotides -- epigenomics -- epigenetics -- Epstein–Barr virus -- hepatitis B virus -- methylation; Epigenesis -- Periodicals; Genomics -- Periodicals; Chromatin -- Periodicals; DNA -- Periodicals; 572.87
• DOI: 10.2217/epi.15.95
• Languages: English
• ISSNs: 1750-1911

Abstract

Aims: To develop a computational resource for viral epigenomic methylation profiles from diverse diseases.Materials & methods: Methylation patterns of Epstein–Barr virus and hepatitis B virus genomic regions are provided as web platform developed using open source Linux-Apache-MySQL-PHP (LAMP) bundle: programming and scripting languages, that is, HTML, JavaScript and PERL.Results: A comprehensive and integrated web resource ViralEpi v1.0 is developed providing well-organized compendium of methylation events and statistical analysis associated with several diseases. Additionally, it also facilitates 'Viral EpiGenome Browser' for user-affable browsing experience using JavaScript-based JBrowse.Conclusion: This web resource would be helpful for research community engaged in studying epigenetic biomarkers for appropriate prognosis and diagnosis of diseases and its various stages.