Consensus guidelines for the diagnosis and management of cryptococcosis and rare yeast infections in the haematology/oncology setting, 2021. (22nd December 2021)

• Record Type: Journal Article
• Authors: Chang, Christina C.; Hall, Victoria; Cooper, Celia; Grigoriadis, George; Beardsley, Justin; Sorrell, Tania C.; Heath, Christopher H.
• Is Part Of: Internal medicine journal. Volume 51(2021)Supplement 7
• Page Start: 118
• Page End: 142
• Publication Date: 2021-12-22
• Subjects: cryptococcosis -- cryptococcal meningitis -- Cryptococcus spp. -- immune reconstitution inflammatory syndrome -- C. gattii; Medicine -- Periodicals; 616
• DOI: 10.1111/imj.15590
• Languages: English
• ISSNs: 1444-0903

Abstract

Abstract: Cryptococcosis caused by the Cryptococcus neoformans – Cryptococcus gattii complex is an important opportunistic infection in people with immunodeficiency, including in the haematology/oncology setting. This may manifest clinically as cryptococcal meningitis or pulmonary cryptococcosis, or be detected incidentally by cryptococcal antigenemia, a positive sputum culture or radiological imaging. Non‐ Candida, non‐ Cryptococcus spp. rare yeast fungaemia are increasingly common in this population. These consensus guidelines aim to provide clinicians working in the Australian and New Zealand haematology/oncology setting with clear guiding principles and practical recommendations for the management of cryptococcosis, while also highlighting important and emerging rare yeast infections and their recommended management.