SP0047 Challenges in the management of different rheumatologic disorders during pregnancy: lessons from the registries. (12th June 2018)

• Record Type: Journal Article
• Authors: Fischer-Betz, R.
• Is Part Of: Annals of the rheumatic diseases. Volume 77(2018)Supplement 2
• Page Start: 13
• Page End: 13
• Publication Date: 2018-06-12
• Subjects: Rheumatism -- Periodicals; 616.723005
• DOI: 10.1136/annrheumdis-2018-eular.7770
• Languages: English
• ISSNs: 0003-4967

Abstract

Abstract : Registers have considerably expanded our knowledge in many fields of rheumatology. In particular, the Biologics Registers contribute to an enormous increase in knowledge on the "real world" safety of the rapidly growing treatment options. Family planning in the case of RD is a particular challenge in the physician-patient relationship and requires an optimal strategy. The impact of pregnancy on the underlying disease or the impact of maternal disease on the outcome of pregnancy is not yet fully understood. In addition there is still a high unmet need of data on drug safety as women with wish to have children or pregnant women are excluded from registration studies for ethical reasons. Therefore, systematic and prospective observation in daily care is the best possibility to collect data on this subject. Data options range from clinical-based cohort studies (e.g. the PROMISSE study), prospective pregnancy exposure studies (e.g. the MotherToBaby studies) to national birth registries. Recently, pregnancy registers in women with RD have been established in several European countries. Together with other studies, these registers will hopefully add to improved expertise in the future Disclosure of Interest: R. Fischer-Betz Grant/research support from: GSK, UCB, Consultant for: Medac, UCB, Speakers bureau: Abbvie, Chugai, Janssen, Lilly, UCB, Pfizer