Characterisation of teaghrelin-like principles from Assam tea cultivated in Thailand. Issue 1 (22nd December 2021)

• Record Type: Journal Article
• Authors: Li, Yue-Chiun; Tanapichatsakul, Chutima; Pripdeevech, Patcharee; Hwang, Tsong Long; Kuo, Ping-Chung; Tzen, Jason T. C.
• Is Part Of: Natural product research. Volume 36:Issue 1(2022)
• Page Start: 305
• Page End: 311
• Publication Date: 2021-12-22
• Subjects: Camellia sinensis var. assamica -- Assam tea -- acylated flavonoid tetraglycoside -- spectroscopic and spectrometric analysis -- ghrelin receptor affinity; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2020.1779715
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: Teaghrelins were identified as unique acylated flavonoid tetraglycosides and firstly reported in Chin-shin oolong tea. In the present study, two new teaghrelin-like compounds (1 and 2 ) were purified and characterised from Assam tea varieties collected in Thailand. Their chemical structures were constructed by the spectroscopic and spectrometric analysis. These two teaghrelin-like compounds were also not supposed to exhibit significant ghrelin receptor affinity according to the structural comparison with those teaghrelin-like compounds previously reported. In addition, compounds 1 and 2 did not display notable anti-inflammatory activity in human neutrophils assay.