A case of Jarisch–Herxheimer reaction in candidiasis treated with systemic fluconazole. Issue 2 (17th February 2020)

• Record Type: Journal Article
• Authors: Muscianese, Marta; Magri, Francesca; Pranteda, Giulia; Pranteda, Guglielmo
• Is Part Of: Dermatologic therapy. Volume 33:Issue 2(2020)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2020-02-17
• Subjects: candidiasis -- fluconazole -- Jarisch–Herxheimer reaction; Skin -- Diseases -- Periodicals; Dermatology -- Periodicals; 616.5
• DOI: 10.1111/dth.13244
• Languages: English
• ISSNs: 1396-0296

Abstract

Abstract: Jarisch–Herxheimer reaction (JHR) is an acute and self‐limited condition, which commonly occurs after treatment for spirochetal infections. Probably, it corresponds to a transient immunological reaction to endotoxin‐like products released from the microorganism during the therapy. For this reason, JHR may be associated with many other infectious diseases besides syphilis. Here, we report a case of a patient affected by extended cutaneous candidiasis diagnosed by culture examination; a JHR occurred after an accidental overdose of oral fluconazole.