Extensive Extramedullary Hematopoiesis in Thalassemia: Soft Tissue Uptake on 99mTc-MDP SPECT/CT. (October 2020)

• Record Type: Journal Article
• Authors: Usmani, Sharjeel; Ahmed, Najeeb; Muzaffar, Samreen; Al Kandari, Fareeda
• Is Part Of: Clinical nuclear medicine. Volume 45:Number 10(2020)
• Publication Date: 2020-10
• Subjects: 99mTc-MDP bone scan -- extramedullary hematopoiesis -- SPECT/CT -- thalassemia; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000003191
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: We report the case of a 45-year-old man with thalassemia major referred for a bone scan as a workup for generalized bone pain. 99m Tc-MDP SPECT CT showed multiple elongated soft tissue masses along the inner aspects of ribs and along both sides of dorsal spine with calcification and mild tracer uptake. There was also a large lobulated presacral soft tissue mass displacing the bladder and involving the adjacent pelvic bone. Biopsy of mildly avid tracer uptake in pelvic soft tissue mass was extramedullary hematopoiesis confirmed by biopsy.