Chemical and biological properties of puffed Dendrobium officinale extracts: Evaluation of antioxidant and anti-fatigue activities. (October 2020)

• Record Type: Journal Article
• Authors: Kim, Singeun; Jo, Kyungae; Byun, Bum Sun; Han, Sung Hee; Yu, Kwang-Won; Suh, Hyung Joo; Hong, Ki-Bae
• Is Part Of: Journal of functional foods. Volume 73(2020)
• Publication Date: 2020-10
• Subjects: Dendrobium officinale -- Antioxidant activity -- Anti-fatigue -- Explosive puffing -- Forced swimming test; Functional foods -- Analysis -- Periodicals; Food -- Biotechnology -- Periodicals; Nutrition -- Periodicals; 613.2
• DOI: 10.1016/j.jff.2020.104144
• Languages: English
• ISSNs: 1756-4646

Abstract

Graphical abstract: Highlights: Puffed DOE showed increased carbohydrate, polyphenol, flavonoid, phytosterol yield. Phytosterol content was significantly higher in puffed extract than a raw extract. High dose of puffed DOE showed a longer swimming time than NOR DOE. Puffed DOE showed better antioxidant activities in liver. Puffed DOE showed significantly higher gene expressions in an energy metabolism. Abstract: Dendrobium officinale ( D. officinale, DO) is a traditional medicinal herb used in China. Phytochemicals and its antioxidant activity of puffed dendrobium extract was measured for antioxidant capacity. Physiological mechanism on skeletal muscle was analyzed by blood glucose, lactic acid, glycogen and ATP content and mRNA gene expression. Antioxidant effect of the extract on liver were measured. The extraction yield and phytochemical contents in DO extract were increased by the change of puffing pressure. In addition, antioxidant activities creased after explosive puffing process. DO extract treated with explosive puffing at high dose was significantly prolonged in swimming time. The glycogen content of puffing DO at high dose was significantly different. The expression of the PGC1-α and the level of ATP in PHD was higher. Explosive puffing DO strongly improve fatigue resistance of mice correlated with inhibiting the depletion of glycogen stores, regulating oxidation related enzymes, and modulating the activation of PGC-1α.