Paraganglioma in pregnancy: A case series and literature review. (March 2022)

• Record Type: Journal Article
• Authors: Eccles-Smith, Jade; Hopkins, Stephanie; Conn, Jennifer; Johnston, Stephanie; Szabo, Rebecca; Price, Sarah; Nankervis, Alison
• Is Part Of: Obstetric medicine. Volume 15:Number 1(2022)
• Page Start: 19
• Page End: 24
• Publication Date: 2022-03
• Subjects: Paraganglioma -- catecholamines -- hypertension -- pregnancy outcomes; Pregnancy -- Complications -- Periodicals; Obstetrics -- Periodicals; 618.2
• DOI: 10.1177/1753495X211006012
• Languages: English
• ISSNs: 1753-495X

Abstract

Paragangliomas are rare neuroendocrine neoplasms which are often catecholamine-secreting and associated with familial syndromes. Described here are three women with a variety of pathology: isolated secretory paraganglioma diagnosed in pregnancy, secretory metastatic paraganglioma in pregnancy and non-secretory metastatic paraganglioma in pregnancy. Whilst paragangliomas are associated with morbidity and mortality during pregnancy, good maternal and fetal outcomes can be achieved through individualised care within the context of a multidisciplinary team. Although paragangliomas are associated with morbidity and mortality in pregnancy, good maternal and fetal outcomes can be achieved through individualised care within the context of a multidisciplinary team.