Correlation of air-bone gap and size of Enlarged Vestibular Aqueduct in children. (May 2020) - Van Beck, Jenna
Abstract: Objective: Enlarged vestibular aqueduct (EVA) is an inner ear malformation that represents an important cause of pediatric hearing loss. While certain elements in the history or audiogram may suggest EVA, it is most often diagnosed using computed tomography (CT). The present investigation was conducted to determine if the size of the audiometric air-bone gap (ABG) is correlated with the size of the vestibular aqueduct in the pediatric population using three vestibular aqueduct measurements. These included the fundus, midpoint, and porous widths of the vestibular aqueduct. Study design: This is a retrospective cohort study. Setting: This study took place at a tertiary care referral center. Patients: Fifty-five children (33 female; 22 male) with a confirmed diagnosis of unilateral or bilateral EVA as determined by prior imaging of the inner ear were included in the study. Main outcome measures: Associations of EVA measurements with ABGs at 0.5 and 1 kHz were evaluated using Pearson correlation coefficients. Results: All of the correlation coefficients were positive, indicating that as EVA measurements increased so did the ABG. Only the correlation between fundus width and ABG at 1 kHz was not statistically significant. Conclusions: ABGs measured during audiometric testing correlate with the size of the EVA and ABGs can be clinical predictors of the severity of the bony abnormality. These data support the third window theory of conductive hearing loss in pediatric EVA. Highlights: ABGs measured during audiometric testing correlate with the size of the EVA. ABGs can be clinical predictors of the severity of the bony abnormality. The findings of this study support the third window hypothesis for the etiology of CHL in pediatric patients with an EVA.