Interrelations of calcium-regulating hormones during normal pregnancy. Issue 6283 (4th July 1981)
- Record Type:
- Journal Article
- Title:
- Interrelations of calcium-regulating hormones during normal pregnancy. Issue 6283 (4th July 1981)
- Main Title:
- Interrelations of calcium-regulating hormones during normal pregnancy.
- Authors:
- Whitehead, M
Lane, G
Young, O
Campbell, S
Abeyasekera, G
Hillyard, C J
MacIntyre, I
Phang, K G
Stevenson, J C - Abstract:
- Abstract : Profound changes in calcium metabolism occur during pregnancy. The mother has to make available extra calcium for fetal requirements while ensuring that her plasma and bone calcium concentrations are satisfactorily maintained. In a cross-sectional study plasma concentrations of the major calcium-regulating hormones--namely, calcitonin, parathyroid hormone, 25-hydroxyvitamin D (25-OHD), and 1, 25-dihydroxyvitamin D (1, 25-(OH)2D)--were measured to establish their interrelations during normal pregnancy. The major changes observed were increases in the circulating concentrations of 1, 25-(OH)2D and calcitonin. Concentrations of parathyroid hormone and 25-OHD remained within the normal range. The increased concentrations of 1, 25-(OH)2D enable the increased physiological need for calcium to be met by enhancing intestinal absorption of this element. The simultaneous rise in calcitonin opposes the bone-resorbing activities of 1, 25-(OH)2D, thereby protecting the integrity of the maternal skeleton. Maternal calcium homeostasis is thus maintained yet the requirements of the fetus are fulfilled.
- Is Part Of:
- BMJ. Volume 283:Issue 6283(1981)
- Journal:
- BMJ
- Issue:
- Volume 283:Issue 6283(1981)
- Issue Display:
- Volume 283, Issue 6283 (1981)
- Year:
- 1981
- Volume:
- 283
- Issue:
- 6283
- Issue Sort Value:
- 1981-0283-6283-0000
- Page Start:
- 10
- Page End:
- 12
- Publication Date:
- 1981-07-04
- Subjects:
- Medicine -- Periodicals
Medicine -- Periodicals
Medicine
Periodicals
610 - Journal URLs:
- http://www.bmj.com/archive ↗
http://www.jstor.org/journals/09598138.html ↗
http://www.ncbi.nlm.nih.gov/pmc/journals/3/ ↗
http://www.bmj.com/bmj/ ↗
http://www.bmj.com/archive ↗ - DOI:
- 10.1136/bmj.283.6283.10 ↗
- Languages:
- English
- ISSNs:
- 0007-1447
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 20469.xml