Converting biology into clinical benefit: lessons learned from BRAF inhibitors. (August 2015)
- Record Type:
- Journal Article
- Title:
- Converting biology into clinical benefit: lessons learned from BRAF inhibitors. (August 2015)
- Main Title:
- Converting biology into clinical benefit: lessons learned from BRAF inhibitors
- Authors:
- McQuade, Jennifer
Davies, Michael A - Abstract:
- The identification and pharmacological targeting of activating BRAF mutations in melanoma has led to significant improvements in patient outcomes. This perspective paper illustrates the lessons learned from the study of BRAF mutations and the development of BRAF inhibitors. The relevance of these lessons to the development of future targeted therapies is highlighted.
- Is Part Of:
- Melanoma management. Volume 2:Number 3(2015)
- Journal:
- Melanoma management
- Issue:
- Volume 2:Number 3(2015)
- Issue Display:
- Volume 2, Issue 3 (2015)
- Year:
- 2015
- Volume:
- 2
- Issue:
- 3
- Issue Sort Value:
- 2015-0002-0003-0000
- Page Start:
- 241
- Page End:
- 254
- Publication Date:
- 2015-08
- Subjects:
- BRAF -- melanoma -- NRAS -- PI3K–AKT pathway -- resistance -- targeted therapy
Melanoma -- Periodicals
616.99477005 - Journal URLs:
- http://www.futuremedicine.com/toc/mmt ↗
http://www.futuremedicine.com/ ↗ - DOI:
- 10.2217/mmt.15.18 ↗
- Languages:
- English
- ISSNs:
- 2045-0885
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 20459.xml