Recurrent, Multisubtype Posttransplant Lymphoproliferative Disorder Masquerading as Inflammatory Bowel Disease. Issue 1 (10th January 2022)

• Record Type: Journal Article
• Authors: Mussarat, Saad; Houston, Kevin V.; Parekh, Parth J.
• Is Part Of: ACG Case Reports Journal. Volume 9:Issue 1(2022)
• Page Start: e00734
• Publication Date: 2022-01-10
• DOI: 10.14309/crj.0000000000000734
• Languages: English
• ISSNs: 2326-3253

Abstract

ABSTRACT: Posttransplant lymphoproliferative disorder (PTLD) is a severe posttransplant complication that occurs because of immunosuppression within the first year; however, recurrent PTLD or development of multiple histologic subtypes are rare. Our case demonstrates a renal transplant recipient with rare, recurrent PTLD with multiple histologic subtypes (monomorphic and polymorphic PTLD) despite a previous response to rituximab and resolution of inflammatory changes on endoscopy. It is essential that clinicians maintain a high suspicion for PTLD when caring for patients with previous transplantation and that they have a lower threshold for biopsy with endoscopic findings of nonspecific inflammatory changes.