Variation in human T lymphotropic virus III (HTLV-III) antibodies in homosexual men: decline before onset of illness related to acquired immune deficiency syndrome (AIDS). Issue 6501 (12th October 1985)

• Record Type: Journal Article
• Authors: Biggar, R J; Melbye, M; Ebbesen, P; Alexander, S; Nielsen, J O; Sarin, P; Faber, V
• Is Part Of: BMJ. Volume 291:Issue 6501(1985)
• Page Start: 997
• Page End: 998
• Publication Date: 1985-10-12
• Subjects: Medicine -- Periodicals; Medicine -- Periodicals; Medicine; Periodicals; 610
• DOI: 10.1136/bmj.291.6501.997
• Languages: English
• ISSNs: 0007-1447

Abstract

Abstract : Western blot analysis was used to document the development and changes in human T lymphotropic virus III (HTLV-III) antibody among Danish homosexual men followed longitudinally over three years. Reactivity against p15, p24, and p55 appeared earliest. After seroconversion the antibody concentration fluctuated, but in one instance a steady decline in banding intensity was seen during the 18 months before onset of the acquired immune deficiency syndrome (AIDS) and throughout the remaining eight months of his life.