Occult Colon Adenocarcinoma and Multiple Myeloma Associated With Clostridium septicum Panophthalmitis With Orbital and Chiasmal Extension: A Case Report. Issue 1 (28th September 2021)

• Record Type: Journal Article
• Authors: Ghanouni, Arian; Avila, Sarah A.; Kim, H. Joon
• Is Part Of: Ophthalmic plastic and reconstructive surgery. Volume 38:Issue 1(2022)
• Page Start: e6
• Page End: e10
• Publication Date: 2021-09-28
• Subjects: Eye -- Surgery -- Periodicals; Ophthalmic plastic surgery -- Periodicals; Reconstructive Surgical Procedures -- Periodicals; Ophthalmologic Surgical Procedures -- Periodicals; Ophthalmology -- Periodicals; Surgery -- Periodicals; 617.70592
• DOI: 10.1097/IOP.0000000000002056
• Languages: English
• ISSNs: 0740-9303

Abstract

Abstract : A previously healthy 62-year-old African American female presented with a fulminant orbital cellulitis of the right eye with diffuse scleritis and orbital inflammation extending to the optic chiasm on neuroimaging. She was taken for an emergent orbitotomy with an orbital fat biopsy and started on broad-spectrum intravenous (IV) and topical antibiotics. Within 36 hours of presentation, scleral thinning and a corneal melt ensued, ending in enucleation. Intraoperative cultures were positive for Clostridium septicum, leading to a systemic work-up exposing a previously undiagnosed colon adenocarcinoma and metastatic multiple myeloma. Abstract : This is a case report of a 62-year-old African American female presenting with a fulminant Clostridium septicum panophthalmitis with orbital and chiasmal extension, resulting in the diagnosis of underlying multiple myeloma and colon adenocarcinoma.