767 Correlations between myocardial work parameters and pulse wave velocity. (8th December 2021)

• Record Type: Journal Article
• Authors: Parlavecchio, Antonio; Caminiti, Rodolfo; Vetta, Giampaolo; Colarusso, Luigi; Lofrumento, Francesca; Pelaggi, Giuseppe; Cusma, Maurizio; Zito, Concetta; Micari, Antonio; Di Bella, Gianluca; Carerj, Scipione
• Is Part Of: European heart journal supplements. Volume 23(2021)Supplement G
• Publication Date: 2021-12-08
• Subjects: Cardiology -- Periodicals; Cardiology -- Europe -- Periodicals; 616.12005
• DOI: 10.1093/eurheartj/suab132.007
• Languages: English
• ISSNs: 1520-765X

Abstract

Abstract: Aims: The myocardial work (MW) is a new echocardiographic method, based on the pressure–strain loop, which allows to quantify the cardiac performance. On the other hand, the pulse wave velocity (PWV) evaluates arterial stiffness, knowing that as the stiffness of an artery increases, the transmission velocity of the anterograde and the retrograde sphygmic wave increase. The aim of the study is to evaluate the correlation between MW and PWV parameters. Methods and results: We enrolled 32 healthy patients (mean age: 39 ± 17 years), who underwent transthoracic Doppler echocardiography (TTE). The MW parameters was derived from the strain–pressure loop, including in its calculation the measurement non-invasive arterial pressure, according to standard speckle tracking echocardiography recommendations. The PWV measurement was obtained by tonometry at the level of the common carotid artery and the common femoral artery. None of the parameters measured was pathological according to the normality studies considered. It was found a linear correlation between PWV and global wasted work (GWW) (linear R 2 : 0.603; P = 0.001) and an inverse linear correlation between PWC and global work efficiency (GWE) (linear R 2 : −0.307; P = 0.032). Conclusions: The study highlights the possibility of PWV to predict pre-clinical myocardial changes, given the correlation with GWW and the linear inverse correlation with GWE.