Ocular Manifestations and Visual Outcomes of Behçet's Uveitis in a Thai population. (2nd January 2019)

• Record Type: Journal Article
• Authors: Pathanapitoon, Kessara; Kunavisarut, Paradee; Saravuttikul, Fa-Arun; Rothova, Aniki
• Is Part Of: Ocular immunology and inflammation. Volume 27:Number 1(2019)
• Page Start: 2
• Page End: 6
• Publication Date: 2019-01-02
• Subjects: Behçet's uveitis -- complications -- ocular manifestations -- Thailand -- visual outcomes; Eye -- Diseases -- Immunological aspects -- Periodicals; Eye -- Inflammation -- Periodicals; 617.7
• DOI: 10.1080/09273948.2017.1351570
• Languages: English
• ISSNs: 0927-3948

Abstract

ABSTRACT: Purpose: To report on ocular manifestations and visual outcomes of Thai patients with Behçet's Uveitis (BU). Methods: We reviewed medical records of 50 BU patients (31 males and 19 females). Ocular manifestations, treatment modalities, complications, and visual outcomes were registered. Results: Ocular involvement was bilateral in 76% of patients, resulting in 89 affected eyes. Panuveitis and posterior uveitis were the most common types. Retinal vasculitis was noted in majority of affected eyes and specifically arteritis was noticed in 32/57(56%). Most patients received combination therapy of systemic corticosteroids and immunosuppressive agents (azathioprine 72%). At final visit, VA ≤20/200 was observed in 25 affected eyes (28%). Risk factors for poor visual outcome were poor visual acuity at presentation ( p < 0.001) and development of optic atrophy ( p = 0.01). Conclusions: Typical ocular manifestations of Thai patients with BU consisted of bilateral uveitis affecting posterior eye segment with high rate of complications and frequent visual loss.