Biomimetics: Antimicrobial Microwebs of DNA–Histone Inspired from Neutrophil Extracellular Traps (Adv. Mater. 14/2019). Issue 14 (2nd April 2019)

• Record Type: Journal Article
• Authors: Song, Yang; Kadiyala, Usha; Weerappuli, Priyan; Valdez, Jordan J.; Yalavarthi, Srilakshmi; Louttit, Cameron; Knight, Jason S.; Moon, James J.; Weiss, David S.; VanEpps, J. Scott; Takayama, Shuichi
• Is Part Of: Advanced materials. Volume 31:Issue 14(2019)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2019-04-02
• Subjects: antibiotic resistance -- bacteria E. coli -- biomimetic materials -- DNA nanofiber networks -- neutrophil extracellular traps; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adma.201970097
• Languages: English
• ISSNs: 0935-9648

Abstract

Abstract : Inspired by the macromolecular weapons used by a type of white blood cell to capture and kill bacteria, in article number 1807436, J. Scott VanEpps, Shuichi Takayama, and co‐workers engineer nanofibrillar microwebs composed of DNA and histones that mimic neutrophil extracellular traps (NETs). The microwebs can enhance the killing activity of a last‐resort antibiotic against Escherichia coli even when it harbors a resistance gene.