Bromo Radical‐Mediated Photoredox Aldehyde Decarbonylation towards Transition‐Metal‐Free Hydroalkylation of Acrylamides at Room Temperature. Issue 2 (29th November 2021)

• Record Type: Journal Article
• Authors: Sun, Zhaozhao; Huang, Huawen; Wang, Qiaolin; Deng, Guo‐Jun
• Is Part Of: Advanced synthesis & catalysis. Volume 364:Issue 2(2022)
• Page Start: 453
• Page End: 458
• Publication Date: 2021-11-29
• Subjects: hydroalkylation -- aldehyde decarbonylation -- transition-metal-free -- bromo radical -- acrylamides; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.202101188
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract: Herein, we report a visible‐light‐mediated hydroalkylation reaction of alkenes using easily available aldehydes as alkyl sources via bromo radical‐promoted photoredox decarbonylation. This protocol provides an alternative entry to C( sp 3 )−C( sp 3 ) bond formation and features considerable advantages including mild and clean reaction conditions, obviation for transition‐metal catalyst, and good functional group compatibility. Abstract :