Study on perinatal‐related factors of maternity and newborn in parturients with intrapartum fever in part of Eastern China: A cross‐sectional study. Issue 1 (16th November 2021)

• Record Type: Journal Article
• Authors: Fan, Yuru; Fan, Chong; Mao, Pengyuan; Rui, Can; Wang, Xinyan; Hou, Wenwen; Luan, Ting; Dong, Zhiyong; Li, Ping; Feng, Shanwu; Zeng, Xin
• Is Part Of: Journal of clinical laboratory analysis. Volume 36:Issue 1(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2021-11-16
• Subjects: intrapartum fever -- monocyte to lymphocyte ratio -- neutrophil to lymphocyte ratio -- perinatal period -- platelet to lymphocyte ratio -- vaginal discharge; Diagnosis, Laboratory -- Periodicals; Medical laboratory technology -- Periodicals; 616
• DOI: 10.1002/jcla.24050
• Languages: English
• ISSNs: 0887-8013

Abstract

Abstract: Background: Maternal intrapartum fever has a serious impact on mother and child. However, the corresponding study seems to be in short. Methods: The role of inflammatory cells in patients who were diagnosed with intrapartum fever lived in part of Eastern China was evaluated. The obstetrics outcomes, complete blood cell count (CBC) and thereby converted neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio, monocyte to lymphocyte ratio (MLR), and vaginal secretion were compared in different groups. Results: Prepartum values of white blood cell (WBC), red blood cell (RBC), and hemoglobin (Hb) were all a little higher in the febrile group than in the afebrile group, and postpartum WBC in the afebrile group was still higher while postpartum RBC and Hb were inferior to non‐fever maternity. Postpartum NLR and MLR were all higher in the fever group but not preferred overtly difference before delivery. Additionally, the comparison of WBC, RBC, Hb, platelets, neutrophils, and monocytes in prepartum and postpartum all showed significant differences. Conclusion: The parturition could bring about the value change of CBC and intrapartum fever might aggravate or alleviate this change. Besides, the intrapartum fever might not be caused mainly by infection and the difference between bacteria and fungus could reflect in the CBC. Abstract : Maternal intrapartum fever is a common obstetric disease during birth process and has a serious impact on mother and child. However, corresponding study seems to be in short. A retrospective cohort study was designed to evaluate the role of inflammatory cell in patients who diagnosed with intrapartum fever (defined as temperature over 37.5℃) lived in part of Eastern China. Prepartum value of white blood cell (WBC), red blood cell (RBC), and hemoglobin (Hb) were all a little higher in febrile group than afebrile group, and postpartum WBC in afebrile group still higher while postpartum RBC and Hb were inferior to non‐fever maternity. Postpartum neutrophil to lymphocyte ratio and monocyte to lymphocyte ratio were all higher in fever group but not preferred overtly difference before delivery. Additionally, the comparison of WBC, RBC, Hb, platelets, neutrophils, and monocytes in prepartum and postpartum all showed significant difference. The parturition could bring about the value change of CBC and intrapartum fever might aggravate or alleviate this change. Besides, the intrapartum fever might not be caused mainly by infection and the difference between bacteria and fungus could reflect in the CBC.