Follow-up Reader Response: Intravenous Immunoglobulin Therapy in Patients With Painful Idiopathic Small Fiber Neuropathy. (18th January 2022)

• Record Type: Journal Article
• Authors: Wilder-Smith, Einar; Spoendlin, Julia
• Is Part Of: Neurology. Volume 98:Number 3(2022)
• Page Start: 128
• Page End: 129
• Publication Date: 2022-01-18
• Subjects: Neurology -- Periodicals; Neurology -- Periodicals; Neurologie -- Périodiques; 616.8
• DOI: 10.1212/WNL.0000000000013076
• Languages: English
• ISSNs: 0028-3878

Abstract

Abstract : We thank Dr. Faber and colleagues for their reply. We agree that intravenous immunoglobulin therapy (IVIG) is not a remedy for all patients with idiopathic small fiber neuropathy (I-SFN). However, the study population was nonrepresentative of clinical practice, given the 75% screening exclusion of patients with SFN. Furthermore, the clinical relevance is limited because the reasons for exclusion were not provided, other than the 16% exclusion for autoimmune comorbidities. 1 These are precisely the patients who should be considered for immunotherapy. 2