SARS-CoV-2: Can sunlight exposure reduce the risk of developing severe consequences of COVID-19?. (February 2022)

• Record Type: Journal Article
• Authors: Muhammad, Jibran Sualeh; Siddiqui, Ruqaiyyah; Khan, Naveed Ahmed
• Is Part Of: Computational biology and chemistry. Volume 96(2022)
• Publication Date: 2022-02
• Subjects: SARS-CoV-2 -- UVB radiation -- COVID-19 -- Genetic changes -- Disease severity; Chemistry -- Data processing -- Periodicals; Biology -- Data processing -- Periodicals; Biochemistry -- Data processing; Biology -- Data processing; Molecular biology -- Data processing; Periodicals; Electronic journals; 542.85
• DOI: 10.1016/j.compbiolchem.2021.107602
• Languages: English
• ISSNs: 1476-9271

Abstract

Abstract: Herein it is proposed that sufficient exposure to sunlight (UVB) modulates host gene expression, offering protection against severe consequences of COVID-19. This could be in addition to sunlight (UVB)-mediated protection by directly inactivating the virus and limiting the viral load. It is suggested that inhibition of CCR2, DPP9, HSPA1L, IFNAR2, OAS1, and TYK2 may, in part, explain UVB-mediated protection against severe consequences of COVID-19. Graphical Abstract: ga1