Measurement matters: An individual differences examination of family socioeconomic factors, latent dimensions of children's experiences, and resting state functional brain connectivity in the ABCD sample. (February 2022)

• Record Type: Journal Article
• Authors: DeJoseph, Meriah L.; Herzberg, Max P.; Sifre, Robin D.; Berry, Daniel; Thomas, Kathleen M.
• Is Part Of: Developmental cognitive neuroscience. Volume 53(2022)
• Publication Date: 2022-02
• Subjects: Socioeconomic status -- Adversity -- MNLFA -- Resting state functional connectivity -- Childhood; Cognitive neuroscience -- Periodicals; Developmental neurobiology -- Periodicals; Neuropsychology -- Periodicals; Neuropsychiatry -- Periodicals; 612.8233
• DOI: 10.1016/j.dcn.2021.101043
• Languages: English
• ISSNs: 1878-9293

Abstract

Abstract: The variation in experiences between high and low-socioeconomic status contexts are posited to play a crucial role in shaping the developing brain and may explain differences in child outcomes. Yet, examinations of SES and brain development have largely been limited to distal proxies of these experiences (e.g., income comparisons). The current study sought to disentangle the effects of multiple socioeconomic indices and dimensions of more proximal experiences on resting-state functional connectivity (rsFC) in a sample of 7834 youth (aged 9–10 years) from the Adolescent Brain Cognitive Development (ABCD) study. We applied moderated nonlinear factor analysis (MNLFA) to establish measurement invariance among three latent environmental dimensions of experience (material/economic deprivation, caregiver social support, and psychosocial threat). Results revealed measurement biases as a function of child age, sex, racial group, family income, and parental education, which were statistically adjusted in the final MNLFA scores. Mixed-effects models demonstrated that socioeconomic indices and psychosocial threat differentially predicted variation in frontolimbic networks, and threat statistically moderated the association between income and connectivity between the dorsal and ventral attention networks. Findings illuminate the importance of reducing measurement biases to gain a more socioculturally-valid understanding of the complex and nuanced links between socioeconomic context, children's experiences, and neurodevelopment. Highlights: Measurement biases were found for several environmental measures in the ABCD study. MNLFA tests and adjusts for measurement biases to afford socioculturally-valid conclusions. Parental education and psychosocial threat were uniquely associated with frontolimbic networks. Associations between INR and DAN-VAN connectivity varied by threat experiences.