Knowledge as to cholesterol reduction and use of phytosterol-enriched dietary foods in the general population: Insights from the Hamburg City Health Study. (January 2022)

• Record Type: Journal Article
• Authors: Zyriax, Birgit-Christiane; Borof, Katrin; Walter, Sascha; Augustin, Matthias; Windler, Eberhard
• Is Part Of: Atherosclerosis. Volume 341(2022)
• Page Start: 1
• Page End: 6
• Publication Date: 2022-01
• Subjects: Cholesterol -- Nutrition -- Lifestyle -- Phytosterols -- Cardiovascular risk; Arteriosclerosis -- Periodicals; Electronic journals; 616.136
• DOI: 10.1016/j.atherosclerosis.2021.12.004
• Languages: English
• ISSNs: 0021-9150

Abstract

Abstract: Background and aims: Dietary approaches to lowering cholesterol appear to be common knowledge. However, the marketing of phytosterol-enriched products and their recommendation by guidelines for individuals at increased risk of cardiovascular disease have given rise to concern, since phytosterols may be atherogenic and inappropriately used by healthy individuals of higher social status at low cardiovascular risk. Hence, we have investigated awareness of cholesterol lowering lifestyle measures and attitudes towards consumption of phytosterol-enriched foods. Methods: Data from validated questionnaires supplemented by queries on cholesterol lowering and phytosterol-enriched products were analyzed using data of 7223 participants of the Hamburg City Health Study, an ongoing cohort study of the general population aged 45–74 years. Results: 95.9% of the participants agreed that lifestyle may lower cholesterol and 76.6% claimed knowledge of measures that lower plasma cholesterol. As to effective approaches, 80.2% suggested physical activity, 67.8% reducing dietary fat, followed by sugar-sweetened beverages or stress, increasing water consumption, or dietary fiber and only 16.2% stated statins and 9.3% phytosterol-enriched products. Compared to nonusers, the 2.0% female and 2.8% male individuals regularly using phytosterol-enriched products had a lower educational status, higher cardiovascular risk, but no difference in income and were characterized by adverse dietary habits. The study has been registered in ClinicalTrial.gov (NCT03934957). Conclusions: In the general population awareness of hypercholesterolemia is high but knowledge on how to lower plasma cholesterol does not necessarily follow scientific evidence. There is a trend towards the use of phytosterol-enriched products by individuals at increased cardiovascular risk independent of income. Graphical abstract: Image 1 Highlights: Awareness of hypercholesterolemia is high in the general population. Knowledge as to cholesterol reduction does not follow scientific evidence. Only a minority stated statins and phytosterols as effective measures. Phytosterols were used by individuals at increased cardiovascular risk. Users of phytosterols were characterized by lower education and poor dietary habits.