Heartech® left ventricular partitioning device improves left ventricular systolic function of patients with chronic heart failure post‐myocardial infarction at 1‐year follow‐up. Issue 1 (27th January 2021)

• Record Type: Journal Article
• Authors: Su, Xiuxiu; Yang, Wenbo; Zhu, Zhengbin; Zhang, Ruiyan; Fang, Yuehua
• Is Part Of: Catheterization and cardiovascular interventions. Volume 99:Issue 1(2022)
• Page Start: 50
• Page End: 56
• Publication Date: 2021-01-27
• Subjects: echocardiography -- heart failure -- left ventricular partitioning device -- myocardial infarction -- percutaneous ventricular restoration; Heart -- Diseases -- Diagnosis -- Periodicals; Cardiac catheterization -- Periodicals; 616.1207572
• DOI: 10.1002/ccd.29489
• Languages: English
• ISSNs: 1522-1946

Abstract

Abstract: Objectives: This study presents 1‐year follow‐up data of echocardiographic outcomes in patients who received the Heartech® left ventricular (LV) partitioning device (LVPD) (Xinrui Medical Equipment Co. Ltd., Shanghai, China). Background: Our first‐in‐man study of the Heartech® LVPD confirmed its safety and efficacy in patients with chronic heart failure (HF) post‐myocardial infarction (MI) 1 month post‐implantation. This subsequent study reports the echocardiographic outcomes of these patients at 1 year of follow‐up. Methods: Fifteen patients with HF post‐MI from three cardiac intervention centers in China were successfully implanted with the Heartech® LVPD via percutaneous ventricular restoration procedures. Echocardiographic parameters—including LV systolic function, diastolic function, two‐dimensional speckle‐tracking analysis, and right ventricular systolic function—were obtained before device implantation and at 1 month and 1 year postoperatively. Results: There was no deterioration of LV diastolic function, specific strain parameters, or right ventricular function at 1 year. Relative to the echocardiographic parameters recorded before the procedure, the LV ejection fraction (32.47 ± 6.98% vs. 42.5 ± 7.41%; p = .001) was significantly improved at 1 year, while the LV end‐diastolic volume index (106.29 ± 28.01 vs. 83.30 ± 31.71; p = .005) and end‐systolic volume index were significantly reduced (72.47 ± 22.77 vs. 50.00 ± 19.70; p = .001). Conclusions: One‐year echocardiographic follow‐up results confirmed that no deterioration of LV diastolic function or specific strain parameters was observed and LV systolic function was significantly improved in patients with HF post‐MI who were implanted with the Heartech® LVPD.