Histopathologic and immunophenotypic profile of a spontaneous mammary carcinoma in a male Humboldt's white‐fronted capuchin (Cebus albifrons). Issue 1 (12th November 2021)

• Record Type: Journal Article
• Authors: Carvalho, Thaynara Parente de; Oliveira, Ayisa Rodrigues de; Santos, Daniel Oliveira dos; Cassali, Geovanni Dantas; Garcia, Ana Paula Vargas; Pereira, Fernanda Mara Aragão Macedo; Soares‐Neto, Lauro Leite; Silva, Monique Ferreira; Paixão, Tatiane Alves; Santos, Renato Lima
• Is Part Of: Journal of medical primatology. Volume 51:Issue 1(2022)
• Page Start: 49
• Page End: 52
• Publication Date: 2021-11-12
• Subjects: breast cancer -- estrogen receptor -- neotropical primates -- oncology -- progesterone receptor -- wildlife; Primates -- Periodicals; Primates -- Diseases -- Periodicals; Medicine, Experimental -- Periodicals; 616.02738
• DOI: 10.1111/jmp.12553
• Languages: English
• ISSNs: 0047-2565

Abstract

Abstract: A 20‐year‐old male captive Humboldt's white‐fronted capuchin ( Cebus albifrons ) that died accidentally had a small non‐ulcerative mammary nodule diagnosed as a mammary carcinoma. Immunohistochemistry demonstrated that neoplastic cells were positive for pan‐cytokeratin and cytokeratin‐7. Approximately 20% of neoplastic cells were positive for Ki‐67. Neoplastic cells expressed estrogen and progesterone receptors.