Pharmacological management of an aneurysmal bone cyst in Noonan syndrome. (12th April 2021)

• Record Type: Journal Article
• Authors: Jadun, Sarah; Beneng, Kiran; Kwok, Jerry; Sproat, Chris; Patel, Vinod
• Is Part Of: Oral surgery. Volume 15:Number 1(2022)
• Page Start: 93
• Page End: 96
• Publication Date: 2021-04-12
• Subjects: alendronic acid -- anuerysmal bone cyst -- bisphosphonates -- Noonan syndrome; Mouth -- Surgery -- Periodicals; 617.522059
• DOI: 10.1111/ors.12615
• Languages: English
• ISSNs: 1752-2471

Abstract

Abstract: Aim: Noonan syndrome is an uncommon disorder which can present with developmental delay, short stature and cardiac anomalies. Oro‐facial presentation includes giant cell lesions with secondary aneurysmal bone cysts (ABC). The current case report presents an extensive mandibular ABC managed solely by oral bisphosphonates. Material and methods: This is a single retrospective case report. Results: A stark regression of the ABC was evident following the use of oral bisphosphonates with reformation of mandibular integrity. Conclusion: This case reports highlights the potential value of oral bisphosphonate to manage oral pathology such as an ABC.