Comparative Study of Microbiological Profile and Management Outcomes of Acute Endophthalmitis after Microincision Vitrectomy Surgery versus Intravitreal Injections. (4th July 2021)

• Record Type: Journal Article
• Authors: Kannan, Naresh Babu; Sen, Sagnik; Mishra, Chitaranjan; Lalitha, Prajna; Rameshkumar, Gunasekaran; Rajan, Renu P; Arumugam, Karthik Kumar; Ramasamy, Kim
• Is Part Of: Ocular immunology and inflammation. Volume 29:Number 5(2021)
• Page Start: 838
• Page End: 844
• Publication Date: 2021-07-04
• Subjects: Endophthalmitis -- MIVS -- intravitreal injection -- pars plana vitrectomy -- IVI; Eye -- Diseases -- Immunological aspects -- Periodicals; Eye -- Inflammation -- Periodicals; 617.7
• DOI: 10.1080/09273948.2019.1695858
• Languages: English
• ISSNs: 0927-3948

Abstract

ABSTRACT: Purpose : The aim of this study was to evaluate and compare incidence and outcomes of management of acute endophthalmitis after microincision vitrectomy surgery (MIVS) and intravitreal injections (IVIs). Methods : Medical records were retrospectively reviewed from January 2012 to December 2017, and the incidence, clinical and microbiological profiles of acute endophthalmitis were documented. Results : Of 26, 332 MIVS and 24, 143 IVI performed, incidence of acute endophthalmitis in MIVS group was 0.027% (1 in 3761 cases) against 0.054% (1 in 1857 cases) in IVI. Gram-positive organisms were causative in post IVI group as against gram-negative organisms in MIVS group. Conclusion : Incidence of endophthalmitis after IVI is almost twice that after MIVS. A trend toward poorer outcomes in MIVS eyes was observed. Both MIVS and IVI being pars plana procedures warrant similar kind of aseptic precautions.