Cardiometabolic markers among Argentinean normal weight and overweight children with and without central obesity. Issue 8 (5th August 2021)

• Record Type: Journal Article
• Authors: Hirschler, Valeria; Molinari, Claudia; Lapertosa, Silvia; Maccallini, Gustavo; Gonzalez, Claudio D
• Is Part Of: Endocrine connections. Volume 10:Issue 8(2021)
• Page Start: 902
• Page End: 908
• Publication Date: 2021-08-05
• Subjects: central obesity -- schoolchildren -- cardiometabolic markers; Endocrinology -- Periodicals; 616.4005
• DOI: 10.1530/EC-21-0139
• Languages: English
• ISSNs: 2049-3614

Abstract

Abstract : Background: The association between central obesity and cardiometabolic complications justifies exploring its association in normal-weight and overweight/obese (OW/OB) schoolchildren. Objective: To describe cardiometabolic markers in four groups according to BMI/WC categories: (i) normal weight with central OB; (ii) normal weight without central OB; (iii) OW/OB with central OB and (iv) OW/OB without central OB, in a sample of Argentinean schoolchildren. Methods: A cross-sectional study of 1264 Argentinean schoolchildren (624 F), aged 9.5 ± 2.2 years was performed between November 2013 and 2015. Children's anthropometric measures, blood pressure (BP), glucose, lipids, and insulin were measured. Children were divided into four groups: (i) normal weight with central OB; (ii) normal weight without central OB; (iii) OW/OB with central OB and (iv) OW/OB without central OB. Results: The prevalence of normal-weight children without central OB was 64.3% (796), normal weight with central OB 5% (66), OW/OB without central OB 11% (137), and OW/OB with central OB 21% (265). Normal weight with central OB had significantly higher triglycerides than normal-weight children without central OB (86 vs 70 mg/dL, respectively) and OW/OB children without central OB (81 vs 77 mg/dL). Multiple linear regression analyses showed that age, systolic BP, HDL-C, triglycerides, and maternal WC were significantly associated with children's WC; R 2 = 0.50 as well as children's BMI; R 2 = 0.37. Conclusion: This study found that children with central OB might be at future higher cardiometabolic risk than those without central OB independently of the presence of OW/OB. However, future longitudinal studies should be performed to confirm these findings.