Ocular Tuberculosis in Human Immunodeficiency Virus and Systemic Tuberculosis Co-infected Patients. (4th July 2021)

• Record Type: Journal Article
• Authors: Jain, Sahil; Bajgai, Priya; Kaur, Savleen; Dogra, Mohit; Sharma, Aman; Sharma, Kusum; Katoch, Deeksha; Dogra, Mangat R.; Gupta, Vishali; Singh, Ramandeep
• Is Part Of: Ocular immunology and inflammation. Volume 29:Number 5(2021)
• Page Start: 1002
• Page End: 1006
• Publication Date: 2021-07-04
• Subjects: Extrapulmonary tuberculosis -- human immunodeficiency virus -- ocular tuberculosis -- tuberculosis -- disseminated tuberculosis; Eye -- Diseases -- Immunological aspects -- Periodicals; Eye -- Inflammation -- Periodicals; 617.7
• DOI: 10.1080/09273948.2020.1714059
• Languages: English
• ISSNs: 0927-3948

Abstract

ABSTRACT: Purpose : To describe the prevalence and clinical findings of ocular tuberculosis (TB) in Human immunodeficiency virus (HIV) and systemic TB co-infected patients. Methods : In this prospective, observational, non-comparative case series, we included HIV and systemic TB co-infected patients, who underwent a detailed ophthalmic and systemic evaluation. Results : Of 85 patients, ocular tuberculosis was seen in eleven patients and their 16 eyes (12.9%). Without the benefit of eye exam, the diagnosis of disseminated TB was missed in 5/52 (9.6%) and 2/25 (8%) of patients clinically assumed to have pulmonary and Extrapulmonary TB, respectively. Conclusion : HIV patients with the disseminated TB have higher risk for ocular TB. As ocular symptoms are rare, still all of them need a detailed ocular examination to look for active ocular TB which will reclassify isolated pulmonary/extrapulmonary to disseminated TB warranting a detailed systemic examination.