Acupuncture combined with Chinese herbal medicine on non-alcoholic fatty liver disease: A protocol for systematic review and meta-analysis. Issue 51 (23rd December 2021)

• Record Type: Journal Article
• Authors: Ma, Yuan; Sun, Kewei; Cao, Jianzhong; Qin, Xiaowu; Shi, Jiaoling; Li, Huiying; Zhang, Jun; Zhang, Tao
• Is Part Of: Medicine. Volume 100:Issue 51(2021)
• Page Start: e28083
• Publication Date: 2021-12-23
• Subjects: acupuncture -- Chinese herbal medicine -- meta-analysis -- non-alcoholic fatty liver disease -- protocol -- systematic review; Medicine -- Periodicals; Medicine -- Periodicals; Médecine -- Périodiques; Geneeskunde; Medicine; Periodicals; Periodicals; 610.5
• DOI: 10.1097/MD.0000000000028083
• Languages: English
• ISSNs: 0025-7974

Abstract

Abstract: Background: Non-alcoholic fatty liver disease (NAFLD) is a global health burden. However, there are no approved drugs for NAFLD. A number of studies have shown that acupuncture combined with Chinese herbal medicine (CHM) can be beneficial for NAFLD. However, high-quality trials are still lacking. Therefore, we aimed to conduct a systematic review and meta-analysis to assess the effectiveness and safety of acupuncture combined with CHM for NAFLD. Methods: Eight electronic databases including PubMed, the Cochrane Library, Web of Science, EMBASE, China National Knowledge Infrastructure, Chinese Scientific and Technical Journals Database, and Wan-fang Database from inception to November 2021 will be searched. We will also search for Clinical Trials Registry Platforms as a supplement. Randomized controlled trials on acupuncture combined with CHM for NAFLD will be included. Literature screening, data extraction, and risk of bias assessment were independently conducted by 2 reviewers. All differences between the 2 reviewers will be discussed and resolved by a third reviewer. Revman5.3 software will be used for meta-analysis. Result: This study aimed to evaluate the effectiveness and safety of acupuncture combined with CHM for NAFLD. Conclusion: The findings of this study will provide more evidence to determine whether acupuncture combined with CHM for NAFLD is an effective and safe intervention for NAFLD.